Determining The Level Of Some Essential Trace Elements : Current School News

Determining The Level Of Some Essential Trace Elements (Selenium, Copper, Zinc And Iodine) In Patients Suffering From Cardiac Diseases.

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Determining The Level Of Some Essential Trace Elements (Selenium, Copper, Zinc And Iodine) In Patients Suffering From Cardiac Diseases.

INTRODUCTION

Background of study

The heart like any other muscle in the body needs an adequate blood supply to provide oxygen so that the muscle can contract and pump blood to the rest of the body. Not only does the heart pump blood to the rest of the body, it also pumps blood to itself via the coronary arteries.

These arteries originate from the base of the aorta (the major blood vessel that carries oxygenated blood from the heart) and then branch out along the surface of the heart.

When the above functions are not reached, it leads to a condition called cardiac disease. Cardiac(heart) disease describes a range of conditions that affect the heart.

Diseases under the heart disease umbrella include blood vessel diseases, such as coronary artery disease, heart rhythm problems (arrhythmias) and heart defects one is born with (congenital heart defects) (Kathiresan et al., 2012).

The established and proposed risk factors for cardiac diseases include age, gender, family history of cardiac disease, dyslipidemia, hypertension, diabetes mellitus, obesity,cigarette smoking, dietary pattern and increased thrombogenicity (Anderson et al., 2011).

Also there is strong evidence that oxidative free radicals have a role in the development of degenerative diseases including cardiovascular diseases(Pyrola et al., 2009).

Trace elements are heavy metals that must be essentially present in body fluids in man at very low levels for metabolic processes. They are present in the body in ng quantities. Example of trace elements include zinc, coper, selenium and iodine.

REFERENCES

Abernathy, C.O, Cantilli, R and Du, H (2008).Essentiality versus toxicity. Some considerations in the risk assessment of essential trace elements in; saxenjed. Hazard Assessment of Chemical.14(6):81-113.

Adedoyin, R.A., Afolabi, A., Adegoke O.O, Akintomide A.O and Awotidebe, T.O (2013). Relationship between socioeconomic status and metabolic syndrome  among Nigerian adults. Diabetes Metabolic Syndrome. 7(2):91–94.

Anderson, K., Odell, P., Wilson, P and Kannel, W.B. (2011) Heart disease risk    profiles. American Heart Journal, 121(6):293–298.

Arthur, J. R., Nicol, F and Beckett G. J.(2010) . Hepatic iodothyronine deiodinase: the role of selenium. Biochemical Journal,  272(7):537-540.

Arthur, J.R and Beckett, G.R.(2016) . Selenium deficiency and thyroid hormone metabolism. Selenium In Biology and Medicine. 24(6):90-95.

Arthur, J.R., Nicol, F and Beckett, G.J. (2009) Hepatic iodothyronine deiodinase: the role of selenium. Biochemical Journal, 272(10):537-540.

Aviram, M and Fuhrman,  B. (2008) LDL oxidation by arterial wall macrophages depends on the oxidative    status in the lipoprotein and in the cells: Role of  prooxidants vs. antioxidants. Molecular and CellularBiochemistry, 188(4):149–159.

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